Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26229442 | 0.87 | PKM (0.36) | TSHRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL26229441 | 0.87 | MEN1 (0.38) | TSHRALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL26545444 | 0.82 | TSHR (0.44) | TSHRCDK2CDK5GSK3BALDH1A1 | |
| SCHEMBL26209321 | 0.80 | KDM4E (0.38) | TSHRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL26545442 | 0.79 | HTT (0.42) | TSHRGSK3BALDH1A1RAB9ANPC1 | |
| SCHEMBL26545440 | 0.78 | DEGS1 (0.42) | GSK3BALDH1A1RAB9ANPC1POLB | |
| SCHEMBL26545741 | 0.75 | EGLN2 (0.34) | TSHRGRM5 | |
| SCHEMBL26545438 | 0.75 | EGLN2 (0.34) | TSHR | |
| SCHEMBL20263247 | 0.70 | EGFR (0.33) | EGFRKDRGRM5 | |
| SCHEMBL24606323 | 0.68 | TSHR (0.32) | TSHRGSK3BEGFRKDRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168194-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |