Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 7/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26235125 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2HTTHSD17B10MAPTMEN1 | |
| SCHEMBL26200121 | 0.70 | KDR (0.47) | SMN1; SMN2HTTHPGDHSD17B10MAPT | |
| SCHEMBL26200122 | 0.68 | EGFR (0.44) | SMN1; SMN2HTTRAB9AHPGDNPC1 | |
| SCHEMBL26545444 | 0.68 | TSHR (0.44) | HTTHPGDHSD17B10MAPTMEN1 | |
| SCHEMBL24942298 | 0.67 | MEN1 (0.35) | SMN1; SMN2HTTRAB9AMAPTGAA | |
| SCHEMBL26200123 | 0.67 | DEGS1 (0.44) | SMN1; SMN2HTTRAB9ANPC1GAA | |
| SCHEMBL26545442 | 0.65 | HTT (0.42) | SMN1; SMN2HTTRAB9AHPGDNPC1 | |
| SCHEMBL26206072 | 0.65 | KDR (0.47) | SMN1; SMN2HPGD | |
| SCHEMBL26200119 | 0.64 | EGFR (0.52) | SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL21879270 | 0.64 | ALDH1A1 (0.57) | SMN1; SMN2HTTRAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168194-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |