Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26206065 | 0.86 | KDR (0.44) | SMN1; SMN2KDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL26209321 | 0.85 | KDM4E (0.38) | SMN1; SMN2KDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL26825431 | 0.83 | KDM4E (0.36) | SMN1; SMN2KDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL26206072 | 0.75 | KDR (0.47) | SMN1; SMN2KDM4EALDH1A1KDR | |
| SCHEMBL26229447 | 0.75 | KCNQ3 (0.38) | SMN1; SMN2HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL26235345 | 0.73 | LCK (0.35) | KDM4ETSHRMAPK1CSNK2A2CSNK2A1 | |
| SCHEMBL26206080 | 0.69 | EGFR (0.46) | SMN1; SMN2KDM4EALOX15KDR | |
| SCHEMBL26206074 | 0.68 | EGFR (0.50) | SMN1; SMN2KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL26206088 | 0.67 | NPC1 (0.48) | SMN1; SMN2ALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL26229442 | 0.64 | PKM (0.36) | KDM4EALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |