Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26229875 | 0.88 | TMPRSS2 (0.37) | POLRMTTMPRSS2TSHRDOT1L | |
| SCHEMBL25388404 | 0.86 | TMPRSS2 (0.38) | POLRMTTMPRSS2 | |
| SCHEMBL26229812 | 0.85 | POLRMT (0.35) | POLRMTTMPRSS2DOT1L | |
| SCHEMBL26230341 | 0.82 | POLRMT (0.49) | POLRMTDOT1L | |
| SCHEMBL26229868 | 0.81 | POLRMT (0.34) | POLRMTTMPRSS2 | |
| SCHEMBL26229754 | 0.80 | — | — | |
| SCHEMBL26287321 | 0.80 | CYP3A4 (0.42) | POLRMT | |
| SCHEMBL26230093 | 0.79 | POLRMT (0.48) | POLRMTDOT1L | |
| SCHEMBL26235345 | 0.79 | LCK (0.35) | POLRMTTMPRSS2TSHR | |
| SCHEMBL25389634 | 0.78 | TMPRSS2 (0.33) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168194-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |