Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | POLRMT | O00411 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | FSHR | P23945 | 2/20 | 0.32 |
| ▸ | HCK | P08631 | 3/20 | 0.32 |
| ▸ | SRC | P12931 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26823086 | 0.87 | TMPRSS2 (0.40) | LCKKDRTMPRSS2POLRMTMAPK1 | |
| SCHEMBL26239498 | 0.86 | LCK (0.33) | LCKKDRTMPRSS2MAPK1TSHR | |
| SCHEMBL26229875 | 0.86 | TMPRSS2 (0.37) | TMPRSS2POLRMTTSHR | |
| SCHEMBL26832567 | 0.80 | TMPRSS2 (0.37) | LCKKDRTMPRSS2MAPK1 | |
| SCHEMBL26237130 | 0.79 | MAOB (0.31) | LCKKDRTMPRSS2MAPK1MAOB | |
| SCHEMBL26229867 | 0.79 | POLRMT (0.35) | TMPRSS2POLRMTTSHR | |
| SCHEMBL26823411 | 0.79 | TMPRSS2 (0.35) | LCKKDRTMPRSS2 | |
| SCHEMBL26235258 | 0.76 | POLRMT (0.46) | POLRMT | |
| SCHEMBL16708561 | 0.75 | POLRMT (0.48) | POLRMT | |
| SCHEMBL26206065 | 0.74 | KDR (0.44) | LCKKDRMAPK1TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |