Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954108 | 0.77 | MAPT (0.60) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL26231537 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL8337275 | 0.68 | FGFR1 (0.60) | ALDH1A1MAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL13724896 | 0.67 | CYP19A1 (0.50) | ALDH1A1HTTSMN1; SMN2MEN1GALR3 | |
| SCHEMBL22954282 | 0.67 | MAPT (0.37) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2422409 | 0.67 | FGFR1 (0.58) | ALDH1A1MAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL31053163 | 0.66 | ALDH1A1 (0.60) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL1278657 | 0.66 | ALDH1A1 (0.60) | ALDH1A1MAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL1459269 | 0.66 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2MEN1GALR3 | |
| SCHEMBL11677753 | 0.66 | ALDH1A1 (0.50) | ALDH1A1HTTSMN1; SMN2MEN1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | ALDH1A1 1490/4885MAPT 2445/4885MAPK1 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.