Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22954108 | 0.83 | MAPT (0.60) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL22954282 | 0.78 | MAPT (0.37) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL26231536 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL16451131 | 0.69 | ALDH1A1 (0.51) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL922709 | 0.68 | NSD2 (0.61) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13724896 | 0.67 | CYP19A1 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2GALR3 | |
| SCHEMBL1944276 | 0.67 | ALDH1A1 (0.39) | ALDH1A1MAPTCHEK1DAPK3GRK5 | |
| SCHEMBL26231539 | 0.67 | GPR35 (0.44) | ALDH1A1MAPTCHEK1DAPK3GRK5 | |
| SCHEMBL1945574 | 0.66 | ALDH1A1 (0.38) | ALDH1A1CHEK1DAPK3GRK5LIMK1 | |
| SCHEMBL25425730 | 0.66 | SMN1; SMN2 (0.51) | ALDH1A1MAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | ALDH1A1 1490/4885MAPT 2445/4885MAPK1 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.