Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26235530 | 0.92 | POLRMT (0.36) | POLRMTDOT1LTNK2RIPK1 | |
| SCHEMBL26235609 | 0.87 | POLRMT (0.34) | POLRMTDOT1L | |
| SCHEMBL26235395 | 0.87 | POLRMT (0.34) | POLRMTDOT1L | |
| SCHEMBL26235249 | 0.86 | POLRMT (0.37) | POLRMTDOT1LRIPK1 | |
| SCHEMBL26235537 | 0.85 | POLRMT (0.36) | POLRMTDOT1L | |
| SCHEMBL26832526 | 0.85 | POLRMT (0.35) | POLRMTDOT1LRIPK1 | |
| SCHEMBL26235533 | 0.84 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL26235390 | 0.83 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL26235392 | 0.82 | POLRMT (0.35) | POLRMTDOT1L | |
| SCHEMBL26235338 | 0.82 | POLRMT (0.35) | POLRMTDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |