⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262284 | 0.83 | — | — | |
| SCHEMBL3155950 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL9237 | 0.69 | — | — | |
| SCHEMBL15457618 | 0.69 | — | — | |
| SCHEMBL3678393 | 0.69 | — | — | |
| SCHEMBL6442399 | 0.69 | — | — | |
| SCHEMBL4754739 | 0.68 | LMNA (0.37) | — | |
| SCHEMBL262361 | 0.68 | — | — | |
| SCHEMBL302897 | 0.67 | CA1 (0.39) | — | |
| SCHEMBL2108202 | 0.67 | CA1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834520-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-05 | — | — | US | disclosed |
| US-9558863-B2 | Electrically conductive polymers with enhanced conductivity | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2017-01-31 | — | — | US | disclosed |
| US-20160229814-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-08-11 | — | — | US | disclosed |
| US-9243111-B2 | Water-soluble electrically conductive polymers | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2016-01-26 | — | — | US | disclosed |
| EP-2975031-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-20150083977-A1 | ELECTRICALLY CONDUCTIVE POLYMERS WITH ENHANCED CONDUCTIVITY | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2015-03-26 | — | — | US | disclosed |
| US-8920681-B2 | Electrically conductive polymers with enhanced conductivity | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2014-12-30 | — | — | US | disclosed |
| US-8772277-B2 | Nitrogen-containing heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-07-08 | — | — | US | disclosed |
| US-20140077135-A1 | WATER-SOLUBLE ELECTRICALLY CONDUCTIVE POLYMERS | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2014-03-20 | — | — | US | disclosed |
| US-8535571-B2 | Water-soluble electrically conductive polymers | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2013-09-17 | — | — | US | disclosed |
| EP-1863780-A1 | PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | Pharmacia & Upjohn Company LLC (US) | 2007-12-12 | — | — | EP | disclosed |
| EP-1831154-A2 | PREPARATION OF PREGABALIN AND RELATED COMPOUNDS | Warner-Lambert Company LLC (US) | 2007-09-12 | — | — | EP | disclosed |
| US-20070141684-A1 | Preparation of gamma-amino acids having affinity for the alpha-2-delta protein | PFIZER INC | 2007-06-21 | — | — | US | disclosed |
| EP-1768952-A2 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | Warner-Lambert Company LLC (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006100568-A1 | PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
| WO-2006100606-A2 | PREPARATION OF BETA-AMINO ACID PRECURSORS VIA INDIUM (III) MEDIATED MARKOVNIKOV ADDITION AND KNOEVENAGEL CONDENSATION | WARNER-LAMBERT COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
| WO-2006008612-A2 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | WARNER-LAMBERT COMPANY LLC (US) | 2006-01-26 | — | — | WO | disclosed |
| WO-2006000904-A2 | PREPARATION OF PREGABALIN AND RELATED COMPOUNDS | WARNER-LAMBERT COMPANY LLC (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050283023-A1 | Preparation of pregabalin and related compounds | HU SHANGHUI | 2005-12-22 | — | — | US | disclosed |
| US-20050228190-A1 | C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin | BAO JIAN | 2005-10-13 | — | — | US | disclosed |