Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.35 |
| ▸ | POLRMT | O00411 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26239647 | 0.90 | DOT1L (0.36) | DOT1LPOLRMT | |
| SCHEMBL24606280 | 0.89 | DOT1L (0.35) | CSNK2A2CSNK2A1DOT1LPOLRMT | |
| SCHEMBL26239615 | 0.89 | DOT1L (0.36) | DOT1LPOLRMT | |
| SCHEMBL24606310 | 0.89 | DOT1L (0.36) | CSNK2A2CSNK2A1DOT1LPOLRMT | |
| SCHEMBL24606316 | 0.87 | DOT1L (0.34) | CSNK2A2CSNK2A1DOT1LPOLRMT | |
| SCHEMBL24606262 | 0.87 | DOT1L (0.36) | CSNK2A2CSNK2A1DOT1LPOLRMT | |
| SCHEMBL26027103 | 0.87 | DOT1L (0.36) | CSNK2A2CSNK2A1DOT1LPOLRMT | |
| SCHEMBL24606327 | 0.86 | DOT1L (0.34) | DOT1LPOLRMT | |
| SCHEMBL26320701 | 0.85 | DOT1L (0.34) | DOT1LPOLRMT | |
| SCHEMBL24606256 | 0.85 | DOT1L (0.34) | DOT1LPOLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |