Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.34 |
| ▸ | POLRMT | O00411 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | PRKCB | P05771 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | PRKCH | P24723 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24606280 | 0.89 | DOT1L (0.35) | DOT1LPOLRMT | |
| SCHEMBL26027103 | 0.89 | DOT1L (0.36) | DOT1LPOLRMTRIPK1 | |
| SCHEMBL24606262 | 0.89 | DOT1L (0.36) | DOT1LPOLRMTRIPK1 | |
| SCHEMBL24606310 | 0.87 | DOT1L (0.36) | DOT1LPOLRMTRIPK1 | |
| SCHEMBL24606309 | 0.86 | IARS1 (0.38) | DOT1LPOLRMT | |
| SCHEMBL24606316 | 0.86 | DOT1L (0.34) | DOT1LPOLRMTRIPK1 | |
| SCHEMBL26237796 | 0.85 | CSNK2A2 (0.35) | DOT1LPOLRMT | |
| SCHEMBL24606327 | 0.84 | DOT1L (0.34) | DOT1LPOLRMT | |
| SCHEMBL24791261 | 0.84 | MIF (0.34) | DOT1LPOLRMT | |
| SCHEMBL27122220 | 0.84 | DOT1L (0.34) | DOT1LPOLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022142477-A1 | METHODS AND MODIFIED NUCLEOSIDES FOR TREATING CORONAVIRUS INFECTIONS | SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-07-07 | — | — | WO | disclosed |