Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26239647 | 0.99 | DOT1L (0.36) | DOT1LALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL26320710 | 0.90 | DOT1L (0.34) | DOT1LPOLRMT | |
| SCHEMBL26320701 | 0.90 | DOT1L (0.34) | DOT1LPOLRMT | |
| SCHEMBL26237796 | 0.89 | CSNK2A2 (0.35) | DOT1LPOLRMT | |
| SCHEMBL26320453 | 0.83 | CYP3A4 (0.36) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL26027103 | 0.82 | DOT1L (0.36) | DOT1LPOLRMT | |
| SCHEMBL26328941 | 0.81 | DOT1L (0.37) | DOT1LAHCYPOLRMT | |
| SCHEMBL26240164 | 0.80 | DOT1L (0.34) | DOT1LPOLRMT | |
| SCHEMBL26235395 | 0.79 | POLRMT (0.34) | DOT1LHTTPOLRMTSMN1; SMN2LMNA | |
| SCHEMBL25723098 | 0.79 | DOT1L (0.33) | DOT1LALDH1A1POLRMTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |