SCHEMBL26237954

SCHEMBL26237954

CCC(C)COC(=O)OC[C@]1(C#N)CCC(c2ccc3c(N)ncnn23)O1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.33
▸ AXL P30530 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26240281 0.93 POLRMT (0.33) POLRMTAXL
SCHEMBL26239790 0.90 POLRMT (0.35) POLRMT
SCHEMBL26237143 0.88 POLRMT (0.33) POLRMT
SCHEMBL26237759 0.87 POLRMT (0.33) POLRMT
SCHEMBL26238101 0.86 POLRMT (0.34) POLRMTAXL
SCHEMBL26237826 0.85 POLRMT (0.35) POLRMT
SCHEMBL26240401 0.85 POLRMT (0.33) POLRMTAXL
SCHEMBL26240249 0.85 POLRMT (0.34) POLRMTAXL
SCHEMBL26237178 0.84 POLRMT (0.34) POLRMT
SCHEMBL26237462 0.84 POLRMT (0.34) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023168254-A1 ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-09-07 — — WO disclosed
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