Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26237826 | 0.91 | POLRMT (0.35) | POLRMT | |
| SCHEMBL26237759 | 0.91 | POLRMT (0.33) | POLRMTDOT1L | |
| SCHEMBL26240281 | 0.91 | POLRMT (0.33) | POLRMT | |
| SCHEMBL26238101 | 0.91 | POLRMT (0.34) | POLRMT | |
| SCHEMBL26237954 | 0.90 | POLRMT (0.33) | POLRMT | |
| SCHEMBL26240541 | 0.89 | POLRMT (0.33) | POLRMTCSNK2A2CSNK2A1 | |
| SCHEMBL26240401 | 0.89 | POLRMT (0.33) | POLRMTDOT1L | |
| SCHEMBL26237143 | 0.89 | POLRMT (0.33) | POLRMT | |
| SCHEMBL26240249 | 0.89 | POLRMT (0.34) | POLRMT | |
| SCHEMBL26237462 | 0.88 | POLRMT (0.34) | POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |