Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040484 | 0.83 | POLB (0.50) | MEN1KMT2AATMGAASMN1; SMN2 | |
| SCHEMBL6892090 | 0.83 | POLB (0.50) | MEN1KMT2AATMGAASMN1; SMN2 | |
| SCHEMBL11353395 | 0.83 | ATM (0.40) | MEN1KMT2AATMGAASMN1; SMN2 | |
| SCHEMBL20110940 | 0.82 | GAA (0.43) | MEN1KMT2AATMGAASMN1; SMN2 | |
| SCHEMBL27810414 | 0.82 | GAA (0.46) | MEN1KMT2AATMGAASMN1; SMN2 | |
| SCHEMBL10313421 | 0.82 | NR3C2 (0.50) | — | |
| SCHEMBL3143535 | 0.82 | MEN1 (0.40) | MEN1KMT2AATMGAASMN1; SMN2 | |
| SCHEMBL12863853 | 0.79 | KMT2A (0.41) | MEN1KMT2AATMGAASMN1; SMN2 | |
| SCHEMBL4470391 | 0.79 | ATM (0.44) | MEN1KMT2AATMGAASMN1; SMN2 | |
| SCHEMBL3533288 | 0.79 | MEN1 (0.49) | MEN1KMT2AATMGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642555-B2 | Prodrugs | KTB TUMORFORSCHUNGSGESELLSCHAFT MBH (DE) | 2014-02-04 | — | — | US | disclosed |
| US-20120094892-A1 | PRODRUGS | KTB TUMORFORSCHUNGSGESELLSCHAFT MBH (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20110117009-A1 | DRUG CONJUGATES WITH POLYGLYCEROLS | FREIE UNIVERSITÄT BERLIN (DE) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094892-A1 | PRODRUGS | ACP3, KLK3, FOLH1 | MEN1 1324/4885KMT2A 2121/4885ATM 2965/4885 |
| US-20110117009-A1 | DRUG CONJUGATES WITH POLYGLYCEROLS | DDOST, STT3A, STT3B | MEN1 1603/4885KMT2A 2736/4885ATM 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.