Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040484 | 0.85 | POLB (0.50) | GAAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL6892090 | 0.85 | POLB (0.50) | GAAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL18121310 | 0.84 | PTGS2 (0.44) | ALDH1A1ATMLMNAKDM4ECYP1A2 | |
| SCHEMBL27810414 | 0.83 | GAA (0.46) | GAAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL2623830 | 0.82 | MEN1 (0.43) | GAAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL20110927 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2APOLBALDH1A1ATM | |
| SCHEMBL18121460 | 0.81 | ALDH1A1 (0.44) | GAAALDH1A1ATMKDM4EHPGD | |
| SCHEMBL4470391 | 0.81 | ATM (0.44) | GAAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL12863853 | 0.81 | KMT2A (0.41) | GAAMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL20110948 | 0.80 | ALDH1A1 (0.33) | GAAKMT2ASMN1; SMN2ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10689335-B2 | Hydrogen sulfide precursors and conjugates thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-06-23 | — | — | US | disclosed |
| US-20180118674-A1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) | 2018-05-03 | — | — | US | disclosed |
| US-20180118674-A1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10689335-B2 | Hydrogen sulfide precursors and conjugates thereof | CBS, TST, STS | GAA 958/4885MEN1 423/4885KMT2A 3590/4885 |
| US-20180118674-A1 | HYDROGEN SULFIDE PRECURSORS AND CONJUGATES THEREOF | CBS, TST, STS | GAA 958/4885MEN1 423/4885KMT2A 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.