SCHEMBL26240747

SCHEMBL26240747

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nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.81
RAB9A P51151 6/20 0.81
NPC1 O15118 5/20 0.81
HTT P42858 5/20 0.81
XBP1 P17861 4/20 0.81
MDM2 Q00987 4/20 0.81
POLB P06746 4/20 0.81
MAPK1 P28482 3/20 0.81
AGTR1 P30556 3/20 0.81
GPR55 Q9Y2T6 3/20 0.81
TERT O14746 1/20 0.81
ALDH1A1 P00352 1/20 0.81
GLA P06280 1/20 0.81
SMN1; SMN2 Q16637 1/20 0.81
TDP1 Q9NUW8 1/20 0.81
PAX8 Q06710 1/20 0.69
RECQL P46063 2/20 0.66
THRB P10828 1/20 0.66
OPRK1 P41145 1/20 0.66
BLM P54132 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Helenalin SCHEMBL161593 0.90 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL161594 0.90 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Mexicanin I SCHEMBL17238871 0.90 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL31237389 0.90 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL10099625 0.90 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL10132557 0.90 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL11030579 0.90 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Bigelovin SCHEMBL29349709 0.82 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Angustibalin SCHEMBL509228 0.82 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
SCHEMBL30578098 0.80 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11752450-B2 Selective extraction method for natural substances D-NATURE CO., LTD. (KR) 2023-09-12 US disclosed