Bigelovin

Bigelovin

SCHEMBL29349709

C=C1C(=O)O[C@H]2C[C@@H](C)[C@@H]3C=CC(=O)[C@@]3(C)[C@@H](OC(C)=O)[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 1.00
RAB9A P51151 6/20 1.00
NPC1 O15118 5/20 1.00
HTT P42858 5/20 1.00
XBP1 P17861 4/20 1.00
MDM2 Q00987 4/20 1.00
MAPK1 P28482 3/20 1.00
AGTR1 P30556 3/20 1.00
GPR55 Q9Y2T6 3/20 1.00
PAX8 Q06710 1/20 1.00
POLB P06746 4/20 0.81
RECQL P46063 2/20 0.81
THRB P10828 1/20 0.81
OPRK1 P41145 1/20 0.81
BLM P54132 1/20 0.81
NPSR1 Q6W5P4 1/20 0.81
TLR9 Q9NR96 1/20 0.81
TERT O14746 1/20 0.72
ALDH1A1 P00352 1/20 0.72
GLA P06280 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Angustibalin SCHEMBL509228 1.00 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalinmethacrylate SCHEMBL31110639 0.91 MAPT (0.83) MAPTRAB9ANPC1HTTXBP1
SCHEMBL30578098 0.90 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL31237389 0.84 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL10132557 0.84 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL161593 0.84 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL10099625 0.84 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL11030579 0.84 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Helenalin SCHEMBL161594 0.84 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1
Mexicanin I SCHEMBL17238871 0.84 MAPT (1.00) MAPTRAB9ANPC1HTTXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250160332-A1 HERBICIDAL COMBINATIONS AND A METHOD FOR CONTROLLING UNDESIRED VEGETATION UPL EUROPE LTD (GB) 2025-05-22 US claimed
US-11845941-B2 Plants comprising a low copy number of Ri genes KNUD JEPSEN A/S (DK) 2023-12-19 US claimed
WO-2023228060-A1 HERBICIDAL COMBINATIONS AND A METHOD FOR CONTROLLING UNDESIRED VEGETATION UPL MAURITIUS LIMITED (MU) 2023-11-30 WO claimed
CN-114303956-B Lily petiolus in-vitro rapid propagation seedling method 鲁东大学 2023-03-14 CN claimed
CN-115073542-A Method for preparing acteoside from callicarpa bigelovii 苏州永健生物医药有限公司 2022-09-20 CN claimed
CN-114786725-A Compositions containing endogenous cannabinoid mimetics and anti-inflammatory compounds, methods of making and uses thereof 药妆研究有限责任公司 2022-07-22 CN claimed
CN-111758509-B Slope vegetation allocation method suitable for loess hilly area 西北农林科技大学 2022-07-01 CN claimed
CN-109797224-B \\28294Jgoose fat liver related A-FABP gene and molecular marking method 湖南农业大学 2022-06-21 CN claimed
CN-114502183-A Compositions and methods for suppressing pathogenic organisms 韦丹塔生物科学股份有限公司 2022-05-13 CN claimed
CN-114303956-A In-vitro rapid propagation seedling raising method for lilium bigelovii 鲁东大学 2022-04-12 CN claimed
CN-114190177-A Method for increasing yield and efficiency of kiwi fruits 四川省农业科学院园艺研究所 2022-03-18 CN claimed
US-11260020-B2 Topical compositions and methods for reducing oxidative stress KIMBERLY-CLARK WORLDWIDE, INC. (US) 2022-03-01 US claimed
US-20250318491-A1 COMPOSITIONS AND METHODS FOR MINIMIZING NORNICOTINE SYNTHESIS IN TOBACCO NORTH CAROLINA STATE UNIVERSITY (US) 2025-10-16 US disclosed
EP-4612271-A1 CARBOHYDROLYTIC AND LIPOGENIC RECOMBINANT YEASTS Xylome Corporation (US) 2025-09-10 EP disclosed
US-20250228204-A1 METHODS AND COMPOSITIONS RELATED TO IMPROVED NITROGEN UTILIZATION EFFICIENCY IN TOBACCO ALTRIA CLIENT SERVICES LLC (US) 2025-07-17 US disclosed
US-20250223605-A1 COMPOSITIONS AND METHODS FOR PRODUCING TOBACCO PLANTS AND PRODUCTS HAVING REDUCED OR ELIMINATED SUCKERS ALTRIA CLIENT SERVICES LLC (US) 2025-07-10 US disclosed
CN-114026060-A Acrylate derivative, use thereof, and intermediate for production thereof 住友化学株式会社 2022-02-08 CN disclosed
CN-215634880-U Detachable klingenbergia-type umbrella tooth structure 沃德传动(天津)股份有限公司 2022-01-25 CN disclosed
CN-111218523-B Leymus divaricata 7SbChromosome specific molecular marker and application thereof 山东省农业科学院作物研究所 2022-01-25 CN disclosed
CN-108138199-B Plants containing low copy number of RI gene 克鲁德简普森花卉公司 2022-01-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250160332-A1 HERBICIDAL COMBINATIONS AND A METHOD FOR CONTROLLING UNDESIRED VEGETATION GGH, AGXT, GLO1 MAPT 2768/4885RAB9A 2685/4885NPC1 4286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.