Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GNPAT | O15228 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20438348 | 1.00 | PTGS1 (0.46) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL19774718 | 0.91 | PTGS1 (0.42) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL24374682 | 0.89 | PTGS1 (0.45) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL19709736 | 0.88 | PTGS1 (0.65) | PTGS1GSTK1GLO1FNTAFNTB | |
| SCHEMBL23966122 | 0.87 | PTGS1 (0.41) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL24072492 | 0.85 | PTGS1 (0.42) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL19492417 | 0.84 | PTGS1 (0.41) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL24829528 | 0.83 | GSTK1 (0.65) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL19774705 | 0.83 | GSTK1 (0.65) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL18383664 | 0.83 | GSTK1 (0.65) | PTGS1GSTK1GLO1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468563-B1 | COMPOUNDS FOR DELIVERING GLUTATHIONE TO A TARGET AND METHODS OF MAKING AND USING THE SAME | UNIV OREGON STATE (US) | 2023-09-13 | — | — | EP | disclosed |