Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26242512 | 0.79 | ADORA2A (0.44) | ADORA2AADORA1 | |
| SCHEMBL26242506 | 0.78 | CNR1 (0.45) | NOTUMCNR1GPR35 | |
| SCHEMBL26242505 | 0.74 | MAOB (0.44) | CNR1GPR35ADORA2AADORA1 | |
| SCHEMBL26242537 | 0.74 | MAPT (0.43) | SMONOTUM | |
| SCHEMBL26246652 | 0.72 | KMT2A (0.54) | CNR1GPR35ADORA1 | |
| SCHEMBL1262220 | 0.70 | KMT2A (0.33) | NOTUM | |
| SCHEMBL20074790 | 0.69 | SLC34A1 (0.45) | NOTUMSLC34A1KDM1A | |
| SCHEMBL12668067 | 0.67 | KDM4E (0.41) | — | |
| SCHEMBL20075633 | 0.67 | NOTUM (0.41) | NOTUMSLC34A1KDM1A | |
| SCHEMBL13092431 | 0.66 | CHRNA7 (0.42) | NOTUMKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150201-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |