Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20061357 | 0.84 | KMT2A (0.36) | SMN1; SMN2L3MBTL1HSD17B10TP53KMT2A | |
| SCHEMBL410293 | 0.79 | KMT2A (0.45) | SMN1; SMN2KMT2AMEN1CYP3A4HPGD | |
| SCHEMBL12541924 | 0.77 | L3MBTL1 (0.32) | SMN1; SMN2L3MBTL1KMT2AKDM4EPKM | |
| SCHEMBL21938463 | 0.77 | POLB (0.42) | KMT2AMEN1KDM4EPKM | |
| SCHEMBL13687250 | 0.73 | BAZ2B (0.37) | SMN1; SMN2L3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL3321442 | 0.73 | CA12 (0.45) | SMN1; SMN2KMT2AMEN1CYP3A4HPGD | |
| SCHEMBL14436542 | 0.73 | CCR5 (0.31) | SMN1; SMN2L3MBTL1HPGDKDM4EALDH1A1 | |
| SCHEMBL20171667 | 0.72 | — | — | |
| SCHEMBL312212 | 0.72 | L3MBTL1 (0.37) | SMN1; SMN2L3MBTL1KMT2AMEN1CYP3A4 | |
| SCHEMBL6628045 | 0.72 | CSNK1A1 (0.38) | SMN1; SMN2HSD17B10TP53KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295158-A1 | METHOD FOR PREPARING COMPOUND AS PI3K INHIBITOR AND INTERMEDIATE COMPOUND FOR PREPARING SAME | BORYUNG CORPORATION (KP) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295158-A1 | METHOD FOR PREPARING COMPOUND AS PI3K INHIBITOR AND INTERMEDIATE COMPOUND FOR PREPARING SAME | PIK3CA, PIK3CD, PIK3C2B | SMN1; SMN2 3717/4885L3MBTL1 4425/4885HSD17B10 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.