Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22294213 | 0.85 | CHEK1 (0.39) | KDM4EALDH1A1NPC1CNR2CHEK1 | |
| SCHEMBL16417913 | 0.85 | CHEK1 (0.39) | KDM4EALDH1A1NPC1CNR2CHEK1 | |
| SCHEMBL20345927 | 0.82 | CA2 (0.35) | KDM4EALDH1A1NPC1CNR2CHEK1 | |
| SCHEMBL20345940 | 0.81 | CA2 (0.38) | CNR2CHEK1 | |
| SCHEMBL16664138 | 0.75 | CHEK1 (0.39) | CNR2CHEK1 | |
| SCHEMBL26246106 | 0.75 | USP2 (0.41) | KDM4EALDH1A1NPC1CNR2CHEK1 | |
| SCHEMBL10290443 | 0.74 | CHEK1 (0.38) | CNR2CHEK1 | |
| SCHEMBL10290753 | 0.72 | CHEK1 (0.37) | CNR2CHEK1 | |
| SCHEMBL26246900 | 0.71 | CNR2 (0.32) | CNR2CHEK1 | |
| SCHEMBL12352665 | 0.71 | L3MBTL1 (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022183081-A9 | HYDROCINNAMOYL PROTECTED RIBOGUANOSINE PHOSPHORAMIDITES FOR DECREASING DEPYRIMIDINATION FROM ALKYL AMINE EXPOSURE DURING FINAL DEPROTECTION | AGILENT TECHNOLOGIES, INC. (US) | 2023-09-21 | — | — | WO | disclosed |