SCHEMBL2624816

SCHEMBL2624816

CCC/C(C)=C/CC[C@]1(C)Oc2c(c(O)cc3c2CNC3=O)C[C@@H]1O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 10/20 0.33
▸ PPARG P37231 1/20 0.32
▸ FNTA P49354 1/20 0.31
▸ FNTB P49356 1/20 0.31
▸ APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2624846 0.93 APP (0.38) ALOX5APP
SCHEMBL2624847 0.93 APP (0.38) ALOX5APP
SCHEMBL30678564 0.93 APP (0.38) ALOX5APP
SCHEMBL2624862 0.93 APP (0.38) ALOX5APP
SCHEMBL22863219 0.86 PTPN2 (0.42) ALOX5APP
SCHEMBL2624855 0.83 ALOX5 (0.33) ALOX5PPARG
SCHEMBL16900172 0.83 ALOX5 (0.33) ALOX5PPARG
SCHEMBL30678560 0.77 NR1H4 (0.32) ALOX5APP
SCHEMBL908611 0.77 ST6GAL1 (0.41) ALOX5FNTAFNTBAPP
SCHEMBL21538203 0.76 ALOX5 (0.52) ALOX5PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8883462-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2014-11-11 — — US disclosed
US-20120100579-A1 TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-04-26 — — US disclosed
US-8110596-B2 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2012-02-07 — — US disclosed
US-20090216028-A1 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) 2009-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090216028-A1 Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer PLAT, F2R, F12 ALOX5 833/4885PPARG 884/4885FNTA 2972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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