Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2624847 | 1.00 | APP (0.38) | APPALOX5ABCG2NR1H4BACE1 | |
| SCHEMBL2624846 | 1.00 | APP (0.38) | APPALOX5ABCG2NR1H4BACE1 | |
| SCHEMBL2624862 | 1.00 | APP (0.38) | APPALOX5ABCG2NR1H4BACE1 | |
| SCHEMBL2624816 | 0.93 | ALOX5 (0.33) | APPALOX5 | |
| SCHEMBL22863219 | 0.86 | PTPN2 (0.42) | APPALOX5BACE1PTPN1 | |
| SCHEMBL908611 | 0.84 | ST6GAL1 (0.41) | APPALOX5ABCG2NR1H4BACE1 | |
| SCHEMBL30678560 | 0.84 | NR1H4 (0.32) | APPALOX5NR1H4BACE1PTPN1 | |
| SCHEMBL21538203 | 0.83 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL29406154 | 0.83 | APP (0.37) | APPALOX5ABCG2NR1H4BACE1 | |
| SCHEMBL24619670 | 0.82 | APP (0.34) | APPNR1H4BACE1PTPN1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023221797-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-11-23 | — | — | WO | disclosed |