Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2624870 | 0.92 | BACE1 (0.36) | PTGS2APPNR1H4BACE1 | |
| SCHEMBL29725717 | 0.92 | BACE1 (0.36) | PTGS2APPNR1H4BACE1 | |
| SCHEMBL2624871 | 0.92 | BACE1 (0.36) | PTGS2APPNR1H4BACE1 | |
| SCHEMBL29406164 | 0.91 | APP (0.32) | ABCG2APPNR1H4BACE1 | |
| SCHEMBL2624830 | 0.91 | APP (0.32) | ABCG2APPNR1H4BACE1 | |
| SCHEMBL2624848 | 0.91 | APP (0.32) | ABCG2APPNR1H4BACE1 | |
| SCHEMBL2624873 | 0.91 | ALOX5 (0.35) | APPNR1H4BACE1 | |
| SCHEMBL2624874 | 0.89 | PTGS2 (0.34) | PTGS2ACHEAPPNR1H4BACE1 | |
| SCHEMBL2624828 | 0.89 | PTGS2 (0.35) | PTGS2APPNR1H4BACE1 | |
| SCHEMBL2624863 | 0.89 | PTGS2 (0.34) | PTGS2ACHEAPPNR1H4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604697-B1 | Triprenyl phenol compounds, process for their production and use as thrombolysis enhancer | UNIV TOKYO AGRICULTURE & TECHNOLOGY TLO CO LTD (JP) | 2015-07-01 | — | — | EP | disclosed |
| US-8883462-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| US-8883462-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20120100579-A1 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-20120100579-A1 | TRIPRENYL PHENOL COMPOUND, PROCESS FOR PRODUCTION OF TRIPRENYL PHENOL COMPOUND, AND THROMBOLYSIS ENHANCER | TOKYO UNIVERSITY OF AGRICLATURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| US-8110596-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-8110596-B2 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2012-02-07 | — | — | US | disclosed |
| US-20090216028-A1 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2009-08-27 | — | — | US | disclosed |
| US-20090216028-A1 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY TLO CO., LTD. (JP) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216028-A1 | Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer | PLAT, F2R, F12 | ABCG2 506/4885PTGS2 301/4885ACHE 1705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.