Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12754796 | 0.98 | MEN1 (0.41) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL16169883 | 0.98 | MEN1 (0.41) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10301175 | 0.98 | MEN1 (0.41) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL26921080 | 0.94 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL63384 | 0.94 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL19039345 | 0.94 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL31348327 | 0.94 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL20462801 | 0.93 | TSHR (0.33) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10301166 | 0.92 | MEN1 (0.45) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL31187428 | 0.92 | MEN1 (0.45) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835458-B2 | Additive fromulation: reaction product of carbinol functional siloxane surfactant and a carboxylic acid containing compound, particles selected from silica, alumina, borosilicate glass, quartz and zircon dispersed in siloxane | PPG INDUSTRIES OHIO, INC. | 2004-12-28 | — | — | US | claimed |
| US-20040209088-A1 | COATING COMPOSITION HAVING IMPROVED MAR AND SCRATCH PROPERTIES | PPG INDUSTRIES OHIO, INC. | 2004-10-21 | — | — | US | claimed |
| US-20230295433-A1 | SILICONE EMULSION COMPOSITION AND FIBER TREATMENT AGENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-09-21 | — | — | US | disclosed |
| US-11655341-B2 | Method for preparing a radical-polymerizable organopolysiloxane, a radiation-curable organopolysiloxane composition, and a release sheet | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-23 | — | — | US | disclosed |
| US-20180223181-A1 | SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT | DAINIPPON INK & CHEMICALS (JP) | 2018-08-09 | — | — | US | disclosed |
| US-9958578-B2 | Composition for manufacturing contact lenses and method for manufacturing contact lenses by using the same | BENQ MATERIALS CORPORATION (TW) | 2018-05-01 | — | — | US | disclosed |
| US-20180094178-A1 | ORGANOPOLYSILOXANE EMULSION COMPOSITION FOR RELEASE PAPER OR RELEASE FILM, METHOD FOR PRODUCING SAME, AND RELEASE PAPER AND RELEASE FILM | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-04-05 | — | — | US | disclosed |
| US-20180024273-A1 | COMPOSITION FOR MANUFACTURING CONTACT LENSES | BENQ MATERIALS CORPORATION (TW) | 2018-01-25 | — | — | US | disclosed |
| US-9804297-B2 | Material for contact lenses, method for manufacturing contact lenses and contact lenses obtained thereby | BENQ MATERIALS CORPORATION (TW) | 2017-10-31 | — | — | US | disclosed |
| US-20170168197-A1 | COMPOSITION FOR MANUFACTURING CONTACT LENSES AND METHOD FOR MANUFACTUGING CONTACT LENSES BY USING THE SAME | BENQ MATERIALS CORPORATION (TW) | 2017-06-15 | — | — | US | disclosed |
| US-20170038499-A1 | COMPOSITION FOR MANUFACTURING CONTACT LENSES AND METHOD FOR MANUFACTURING CONTACT LENSES BY USING THE SAME | BENQ MATERIALS CORPORATION (TW) | 2017-02-09 | — | — | US | disclosed |
| US-20120001980-A1 | INK JET INK, INK JET RECORDING METHOD, AND INK CARTRIDGE | CANON KABUSHIKI KAISHA (JP) | 2012-01-05 | — | — | US | disclosed |
| US-20110135905-A1 | HIGH ENERGY RAY-CURABLE COMPOSITION | DOW CORNING CORPORATION (US) | 2011-06-09 | — | — | US | disclosed |
| US-20090088488-A1 | Use of linear siloxanes and process for their preparation | EVONIK DEGUSSA GMBH (DE) | 2009-04-02 | — | — | US | disclosed |
| US-7345108-B2 | Additives for imparting mar and scratch resistance and compositions comprising the same | PPG INDUSTRIES OHIO, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| US-7268176-B2 | Additives for imparting mar and scratch resistance and compositions comprising the same | PPG INDUSTRIES OHIO, INC. (US) | 2007-09-11 | — | — | US | disclosed |
| US-20060078748-A1 | Novel additives for imparting Mar and scratch resistance and compositions comprising the same | AMBROSE RONALD R | 2006-04-13 | — | — | US | disclosed |
| US-6835458-B2 | Additive fromulation: reaction product of carbinol functional siloxane surfactant and a carboxylic acid containing compound, particles selected from silica, alumina, borosilicate glass, quartz and zircon dispersed in siloxane | PPG INDUSTRIES OHIO, INC. | 2004-12-28 | — | — | US | disclosed |
| US-20040209088-A1 | COATING COMPOSITION HAVING IMPROVED MAR AND SCRATCH PROPERTIES | PPG INDUSTRIES OHIO, INC. | 2004-10-21 | — | — | US | disclosed |
| US-20040116585-A1 | Novel additives for imparting mar and scratch resistance and compositions comprising the same | PPG INDUSTRIES OHIO, INC. | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180223181-A1 | SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT | ILK, LIMA1, EED | TSHR 4881/4885MEN1 1017/4885KMT2A 478/4885 |
| US-11655341-B2 | Method for preparing a radical-polymerizable organopolysiloxane, a radiation-curable organopolysiloxane composition, and a release sheet | MUS81, MSR1, H1-4 | TSHR 147/4885MEN1 490/4885KMT2A 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.