Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 17/20 | 0.64 |
| ▸ | NMUR1 | Q9HB89 | 16/20 | 0.64 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2625082 | 0.93 | NMUR2 (0.59) | NMUR2NMUR1ABCB11 | |
| SCHEMBL2625075 | 0.91 | NMUR2 (0.53) | NMUR2NMUR1NPY1R | |
| SCHEMBL2625080 | 0.89 | NMUR2 (0.55) | NMUR2NMUR1ABCB11 | |
| SCHEMBL2628463 | 0.88 | NMUR2 (0.63) | NMUR2NMUR1NPY1R | |
| SCHEMBL2625090 | 0.86 | NMUR2 (0.53) | NMUR2NMUR1 | |
| SCHEMBL17226114 | 0.85 | NMUR2 (0.68) | NMUR2NMUR1NPY1R | |
| SCHEMBL2628471 | 0.84 | NMUR2 (0.57) | NMUR2NMUR1 | |
| SCHEMBL2625078 | 0.83 | NMUR2 (0.47) | NMUR2NMUR1NPY1R | |
| SCHEMBL2628482 | 0.82 | NMUR2 (0.56) | NMUR2NMUR1NPY1R | |
| SCHEMBL2628467 | 0.82 | NMUR2 (0.55) | NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120094898-A1 | PEPTIDE DERIVATIVE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094898-A1 | PEPTIDE DERIVATIVE | NPPA, LNPEP, NGLY1 | NMUR2 223/4885NMUR1 200/4885NPY1R 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.