Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26253127 | 0.96 | MEN1 (0.61) | MEN1KMT2AZDHHC20ZDHHC2CASP2 | |
| SCHEMBL5139380 | 0.88 | ZDHHC20 (0.58) | MEN1KMT2AZDHHC20ZDHHC2CASP2 | |
| SCHEMBL4649336 | 0.86 | ZDHHC20 (0.50) | MEN1KMT2AZDHHC20ZDHHC2CASP2 | |
| SCHEMBL26437443 | 0.84 | MEN1 (0.68) | MEN1KMT2AZDHHC20ZDHHC2CASP2 | |
| SCHEMBL17229157 | 0.82 | MEN1 (1.00) | MEN1KMT2ACASP2RECQLNAAA | |
| SCHEMBL13058102 | 0.82 | MEN1 (0.65) | MEN1KMT2AZDHHC20ZDHHC2CASP2 | |
| SCHEMBL20859582 | 0.82 | MEN1 (0.65) | MEN1KMT2AZDHHC20ZDHHC2CASP2 | |
| SCHEMBL6531858 | 0.82 | SMN1; SMN2 (0.41) | MEN1KMT2AZDHHC20ZDHHC2CASP2 | |
| SCHEMBL11528071 | 0.81 | — | — | |
| SCHEMBL11758762 | 0.80 | MEN1 (0.94) | MEN1KMT2ACASP2RECQLNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212180-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | The Scripps Research Institute (US) | 2023-07-19 | — | — | EP | disclosed |