Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.58 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.58 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649336 | 0.94 | ZDHHC20 (0.50) | ZDHHC20ZDHHC2CASP2NAAAEPHX1 | |
| SCHEMBL26253129 | 0.88 | MEN1 (0.68) | ZDHHC20ZDHHC2CASP2NAAAEPHX1 | |
| SCHEMBL11528071 | 0.85 | — | — | |
| SCHEMBL26253127 | 0.84 | MEN1 (0.61) | ZDHHC20ZDHHC2CASP2FAAHMEN1 | |
| SCHEMBL6531858 | 0.82 | SMN1; SMN2 (0.41) | ZDHHC20ZDHHC2CASP2NAAAFAAH | |
| SCHEMBL22104112 | 0.82 | CASP2 (0.59) | ZDHHC20ZDHHC2CASP2NAAAEPHX1 | |
| SCHEMBL10337028 | 0.80 | NQO2 (0.42) | FAAHMEN1KMT2A | |
| SCHEMBL1077291 | 0.79 | ZDHHC20 (0.53) | ZDHHC20ZDHHC2CASP2NAAAEPHX1 | |
| SCHEMBL15223337 | 0.79 | PAOX (0.44) | ZDHHC20ZDHHC2CASP2NAAAFAAH | |
| SCHEMBL17743162 | 0.79 | TSHR (0.55) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086609-A2 | INHIBITORS OF TRYPTASE | AXYS PHARMACEUTICALS, INC. (US) | 2006-08-17 | — | — | WO | claimed |
| US-6376429-B1 | CONTROLLING WEEDS | HOECHST SCHERING AGREVO GMBH (DE) | 2002-04-23 | — | — | US | claimed |
| US-6297196-B1 | HETEROCYCLIC COMPOUNDS WITH KETONE GROUPS AND OXIMES, PHOSPHONATES OR PHOSPHATES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-10-02 | — | — | US | claimed |
| EP-1117639-A1 | BENZOYLCYCLOHEXANDIONES, METHOD FOR THE PRODUCTION AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2001-07-25 | — | — | EP | claimed |
| EP-1109807-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2001-06-27 | — | — | EP | claimed |
| US-6211216-B1 | KETONES AS HERBICIDES | AVENTIS CORPSCIENCE GMBH (DE) | 2001-04-03 | — | — | US | claimed |
| WO-2000021924-A1 | BENZOYLCYCLOHEXANDIONES, METHOD FOR THE PRODUCTION AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-04-20 | — | — | WO | claimed |
| WO-2000014087-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-03-16 | — | — | WO | claimed |
| WO-1998006710-A1 | SUBSTITUTED 4-NITROIMINO-PERHYDRO-1,3,5-OXADIAZINE DERIVATIVES, THEIR USE AS PESTICIDES AND INTERMEDIATES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1998-02-19 | — | — | WO | claimed |
| CN-104508563-B | Pattern forming method and the electronic device manufacturing method and electronic device for respectively using it | 富士胶片株式会社 | 2019-05-28 | — | — | CN | disclosed |
| EP-2994156-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES THROUGH INHIBITING TGF- ACTIVITY | Southern Research Institute (US) | 2016-03-16 | — | — | EP | disclosed |
| WO-2014183018-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES THROUGH INHIBITING TGF-β ACTIVITY | SOUTHERN RESEARCH INSTITUTE (US) | 2014-11-13 | — | — | WO | disclosed |
| US-8273740-B2 | antiallergen; not direct way to change nature of immunological response to allergen; G-protein-coupled \"chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2)\" antagonist for prostaglandin PGD2, that mediates PGD2-dependent migration of blood Th2 cells; ; asthma, rhinitis, COPD | ACTELION PHARMACEUTICALS, LTD. (CH) | 2012-09-25 | — | — | US | disclosed |
| US-20080108638-A1 | 2-Sulfanyl-Benzoimidazol-1-Yl-Acetic Acid Derivatives as Crth2 Antagonists | ACTELION PHARMACEUTICALS,LTD. (CH) | 2008-05-08 | — | — | US | disclosed |
| EP-1109807-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Aventis CropScience GmbH (DE) | 2001-06-27 | — | — | EP | disclosed |
| US-6211216-B1 | KETONES AS HERBICIDES | AVENTIS CORPSCIENCE GMBH (DE) | 2001-04-03 | — | — | US | disclosed |
| WO-2001007422-A1 | ISOXAZOLYL- AND ISOXAZOLINYL-SUBSTITUTED BENZOYLCYCLOHEXANEDIONES, PRODUCTION METHOD AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2001-02-01 | — | — | WO | disclosed |
| WO-2000021924-A1 | BENZOYLCYCLOHEXANDIONES, METHOD FOR THE PRODUCTION AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-04-20 | — | — | WO | disclosed |
| WO-2000014087-A1 | BENZOYL DERIVATIVES, METHOD FOR PRODUCING THEM AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS | AVENTIS CROPSCIENCE GMBH (DE) | 2000-03-16 | — | — | WO | disclosed |
| WO-1998006710-A1 | SUBSTITUTED 4-NITROIMINO-PERHYDRO-1,3,5-OXADIAZINE DERIVATIVES, THEIR USE AS PESTICIDES AND INTERMEDIATES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1998-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108638-A1 | 2-Sulfanyl-Benzoimidazol-1-Yl-Acetic Acid Derivatives as Crth2 Antagonists | HRH2, HRH1, HRH3 | ZDHHC20 747/4885ZDHHC2 239/4885CASP2 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.