⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25768995 | 1.00 | — | — | |
| SCHEMBL17445995 | 0.84 | — | — | |
| SCHEMBL26253259 | 0.83 | FBP1 (0.33) | — | |
| SCHEMBL25769000 | 0.83 | FBP1 (0.33) | — | |
| SCHEMBL17123274 | 0.83 | — | — | |
| SCHEMBL12667498 | 0.81 | — | — | |
| SCHEMBL12223696 | 0.81 | — | — | |
| SCHEMBL12090320 | 0.79 | — | — | |
| SCHEMBL24211093 | 0.79 | — | — | |
| SCHEMBL17445985 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230383253-A1 | Lymphocyte Activation Gene 3 (LAG3) Compositions and Methods for Immunotherapy | INTELLIA THERAPEUTICS, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230374456-A1 | T-Cell Immunoglobulin and Mucin Domain 3 (TIM3) Compositions and Methods for Immunotherapy | INTELLIA THERAPEUTICS, INC. (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230287400-A1 | Modified Guide RNAs | INTELLIA THERAPEUTICS, INC. (US) | 2023-09-14 | — | — | US | disclosed |