Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242078 | 0.83 | KCNA4 (0.34) | — | |
| SCHEMBL25671613 | 0.82 | FFAR3 (0.31) | FFAR3 | |
| SCHEMBL22047385 | 0.82 | FFAR3 (0.31) | FFAR3 | |
| SCHEMBL13954120 | 0.76 | ALDH1A1 (0.34) | FFAR3 | |
| SCHEMBL24245894 | 0.76 | FFAR3 (0.35) | FFAR3 | |
| SCHEMBL2605491 | 0.76 | — | — | |
| SCHEMBL13934073 | 0.73 | — | — | |
| SCHEMBL27868339 | 0.73 | EPHX1 (0.39) | EPHX1FFAR3 | |
| SCHEMBL12044442 | 0.72 | FFAR3 (0.38) | FFAR3 | |
| SCHEMBL2625519 | 0.72 | FFAR3 (0.38) | FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163763-B2 | Pyrimidine compounds, compositions and methods of use | GENENTECH, INC. (US) | 2012-04-24 | — | — | US | disclosed |