SCHEMBL26255252

SCHEMBL26255252

C=C[Si](N(C)c1ccccc1)(N(C)c1ccccc1)N(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 1/20 0.39
RELA Q04206 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
FAAH O00519 1/20 0.34
PHGDH O43175 1/20 0.34
MGLL Q99685 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
EGFR P00533 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26255406 0.84 KMT2A (0.38) KMT2AMEN1HTTRELATAAR1
SCHEMBL25175053 0.84 KMT2A (0.38) KMT2AMEN1HTTRELATAAR1
SCHEMBL26255290 0.82 KMT2A (0.37) KMT2AMEN1HTTRELATAAR1
SCHEMBL25174581 0.82 KMT2A (0.37) KMT2AMEN1HTTRELATAAR1
SCHEMBL26255382 0.82 KMT2A (0.37) KMT2AMEN1HTTRELATAAR1
SCHEMBL22344771 0.78 ALDH1A1 (0.36) KMT2AMEN1HTTTAAR1ALDH1A1
SCHEMBL3122245 0.76 KMT2A (0.48) KMT2AMEN1HTTRELAALDH1A1
SCHEMBL25168581 0.74 MEN1 (0.34) KMT2AMEN1HTTTAAR1ALDH1A1
SCHEMBL26255544 0.74 MEN1 (0.34) KMT2AMEN1HTTRELATAAR1
SCHEMBL26255431 0.74 MEN1 (0.39) KMT2AMEN1HTTRELATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230287562-A1 COMPOSITIONS ND METHODS USING SAME FOR GERMANIUM SEED LAYER VERSUM MATERIALS US, LLC 2023-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287562-A1 COMPOSITIONS ND METHODS USING SAME FOR GERMANIUM SEED LAYER GMNN, AGL, GYS2 KMT2A 3049/4885MEN1 2450/4885HTT 2515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.