SCHEMBL26255671

SCHEMBL26255671

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nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.44
PAX8 Q06710 1/20 0.41
DPP8 Q6V1X1 1/20 0.39
DPP7 Q9UHL4 1/20 0.39
CTRB1 P17538 5/20 0.35
SLC15A1 P46059 1/20 0.34
OPRD1 P41143 6/20 0.33
OPRM1 P35372 4/20 0.33
OPRK1 P41145 1/20 0.33
TERT O14746 1/20 0.33
TPSAB1 Q15661 2/20 0.32
PLG P00747 1/20 0.32
PRSS1 P07477 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29589671 0.85 ALDH1A1 (0.50) DPP4PAX8DPP8DPP7CTRB1
SCHEMBL29355244 0.85 ALDH1A1 (0.50) DPP4PAX8DPP8DPP7CTRB1
SCHEMBL10954147 0.84 DPP4 (0.44) DPP4PAX8DPP8DPP7CTRB1
SCHEMBL15840389 0.82 DPP4 (0.42) DPP4PAX8DPP8DPP7CTRB1
Bromide SCHEMBL10957448 0.82 DPP4 (0.42) DPP4PAX8DPP8DPP7CTRB1
SCHEMBL2544527 0.82 ALDH1A1 (0.52) DPP4PAX8DPP8DPP7CTRB1
SCHEMBL11253834 0.82 ALDH1A1 (0.52) DPP4PAX8DPP8DPP7CTRB1
SCHEMBL10952283 0.82 CYP2D6 (0.43) DPP4PAX8DPP8DPP7CTRB1
SCHEMBL10954323 0.82 DPP4 (0.45) DPP4PAX8DPP8DPP7CTRB1
SCHEMBL10955096 0.81 DPP7 (0.44) DPP4PAX8DPP8DPP7CTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3958977-B1 CAMPTOTHECIN DERIVATIVES IMMUNOGEN INC (US) 2023-09-13 EP disclosed