Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589671 | 1.00 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL2544527 | 0.98 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL11253834 | 0.98 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL32680129 | 0.93 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL30585206 | 0.91 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL30585205 | 0.91 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL30585204 | 0.91 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL30637048 | 0.89 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL29906328 | 0.86 | EGFR (0.42) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL29454351 | 0.86 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124212-A1 | MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF | IMMUNOGEN INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-12390471-B2 | Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof | IMMUNOGEN, INC. (US) | 2025-08-19 | — | — | US | disclosed |
| CN-116785450-A | Maytansinoid derivatives with self-cleaving peptide linker and conjugates thereof | 伊缪诺金公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116785451-A | Maytansinoid derivatives with self-cleaving peptide linker and conjugates thereof | 伊缪诺金公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-110366431-B | Maytansinoid derivatives with self-cleaving peptide linker and conjugates thereof | 伊缪诺金公司 | 2023-07-18 | — | — | CN | disclosed |
| US-20220133711-A1 | CAMPTOTHECIN DERIVATIVES | IMMUNOGEN, INC. | 2022-05-05 | — | — | US | disclosed |
| US-20220111067-A1 | MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF | IMMUNOGEN SWITZERLAND GMBH (CH) | 2022-04-14 | — | — | US | disclosed |
| US-11229639-B2 | Camptothecin derivatives | IMMUNOGEN, INC. (US) | 2022-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12390471-B2 | Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof | VIP, AREG, MIF | ALDH1A1 1927/4885LMNA 3531/4885MAPT 3556/4885 |
| US-20220111067-A1 | MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF | VIP, AREG, MIF | ALDH1A1 1927/4885LMNA 3531/4885MAPT 3556/4885 |
| US-20220133711-A1 | CAMPTOTHECIN DERIVATIVES | TOP2A, TOP2B, PCNA | ALDH1A1 1182/4885LMNA 2121/4885MAPT 3921/4885 |
| US-20260124212-A1 | MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF | VEGFA, VIP, AREG | ALDH1A1 2585/4885LMNA 1078/4885MAPT 4002/4885 |
| US-11229639-B2 | Camptothecin derivatives | TOP2A, TOP2B, PCNA | ALDH1A1 1182/4885LMNA 2121/4885MAPT 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.