Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744984 | 0.84 | MAPT (0.42) | MAPTALDH1A1HSD17B10TDP1RAB9A | |
| SCHEMBL736665 | 0.82 | HSD17B10 (0.41) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL14591514 | 0.82 | TSHR (0.50) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL6961971 | 0.81 | POLB (0.46) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL2222086 | 0.81 | PTPN22 (0.53) | — | |
| SCHEMBL20020372 | 0.81 | MAPT (0.40) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL11893039 | 0.79 | NCEH1 (0.44) | MAPTALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL792004 | 0.79 | CYP1A2 (0.53) | TDP1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL11314967 | 0.78 | KDM4E (0.52) | MAPTALDH1A1TDP1RAB9AKDM4E | |
| SCHEMBL30219496 | 0.78 | HSD17B10 (0.38) | MAPTALDH1A1CYP2A6TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760712-B2 | Triarylmethane compounds | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760712-B2 | Triarylmethane compounds | CBR3, HAX1, HRH3 | MAPT 4486/4885ALDH1A1 2431/4885CYP2A6 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.