SCHEMBL26264286

SCHEMBL26264286

Cc1ccc(-c2ccc(C(=O)N[C@@H](CC(=O)O)C(=O)O)o2)cc1

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 14/20 0.73
PRSS1 P07477 2/20 0.54
TMPRSS15 P98073 2/20 0.54
C3AR1 Q16581 1/20 0.50
MMP13 P45452 1/20 0.50
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26264278 0.89 SUCNR1 (0.72) SUCNR1PRSS1TMPRSS15C3AR1
SCHEMBL26264358 0.88 SUCNR1 (0.71) SUCNR1PRSS1TMPRSS15C3AR1
SCHEMBL26263219 0.88 SUCNR1 (0.61) SUCNR1C3AR1MMP13MGAMGAA
SCHEMBL26264363 0.88 SUCNR1 (0.81) SUCNR1PRSS1TMPRSS15C3AR1MMP13
SCHEMBL26264257 0.87 SUCNR1 (0.69) SUCNR1PRSS1TMPRSS15C3AR1
SCHEMBL26264282 0.86 C3AR1 (0.66) SUCNR1PRSS1TMPRSS15C3AR1
SCHEMBL26264373 0.84 SUCNR1 (0.76) SUCNR1PRSS1TMPRSS15C3AR1
SCHEMBL26264369 0.84 SUCNR1 (1.00) SUCNR1PRSS1TMPRSS15C3AR1
SCHEMBL26264366 0.84 SUCNR1 (0.69) SUCNR1PRSS1TMPRSS15C3AR1MMP13
SCHEMBL26264365 0.84 SUCNR1 (0.65) SUCNR1PRSS1TMPRSS15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023183776-A2 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION NEW YORK UNIVERSITY (US) 2023-09-28 WO disclosed
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION UNIV NEW YORK (US) 2023-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION SUCNR1, SYNGR2, TSPO SUCNR1 1/4885PRSS1 1822/4885TMPRSS15 1562/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.