Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 6/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26265232 | 0.95 | CLPP (0.56) | CLPPGPR132CYP3A4CYP2D6DRD2 | |
| SCHEMBL26266368 | 0.84 | CLPP (0.55) | CLPPGPR132CYP3A4CYP2D6DRD2 | |
| SCHEMBL26265235 | 0.83 | CLPP (0.68) | CLPPGPR132CYP3A4CYP2D6DRD2 | |
| SCHEMBL26265217 | 0.81 | CLPP (0.68) | CLPPGPR132CYP3A4CYP2D6DRD2 | |
| SCHEMBL26265059 | 0.81 | CLPP (0.80) | CLPPGPR132CYP3A4CYP2D6DRD2 | |
| SCHEMBL25229114 | 0.80 | CLPP (0.69) | CLPPGPR132CYP3A4CYP2D6DRD2 | |
| SCHEMBL21135034 | 0.80 | CLPP (0.67) | CLPPGPR132CYP3A4CYP2D6DRD2 | |
| SCHEMBL26265164 | 0.80 | CLPP (0.67) | CLPPGPR132CYP3A4CYP2D6DRD2 | |
| SCHEMBL26265230 | 0.80 | CLPP (0.55) | CLPPGPR132CYP3A4CYP2D6DRD2 | |
| SCHEMBL26265233 | 0.79 | CLPP (0.64) | CLPPGPR132CYP3A4CYP2D6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295162-A1 | SYNTHESIS OF NOVEL IMIPRIDONE DERIVATIVES AND THEIR EVALUATION FOR THEIR ANTICANCER ACTIVITY | SEMMELWEIS EGYETEM (HU) | 2023-09-21 | — | — | US | disclosed |
| US-20230295162-A1 | SYNTHESIS OF NOVEL IMIPRIDONE DERIVATIVES AND THEIR EVALUATION FOR THEIR ANTICANCER ACTIVITY | SEMMELWEIS EGYETEM (HU) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295162-A1 | SYNTHESIS OF NOVEL IMIPRIDONE DERIVATIVES AND THEIR EVALUATION FOR THEIR ANTICANCER ACTIVITY | IMPA1, REN, IGF1R | CLPP 3731/4885GPR132 145/4885CYP3A4 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.