SCHEMBL26265696

SCHEMBL26265696

O=C(O)COCCOCCNC(=O)c1cc(B(O)O)cc([N+](=O)[O-])c1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
LMNA P02545 3/20 0.51
MAPT P10636 2/20 0.51
HTT P42858 2/20 0.51
GAA P10253 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.44
PKM P14618 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 3/20 0.39
HPGD P15428 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18356265 0.98 MEN1 (0.53) MEN1KMT2ALMNAMAPTHTT
SCHEMBL26265666 0.91 LMNA (0.49) MEN1KMT2ALMNAMAPTHTT
SCHEMBL18355961 0.89 LMNA (0.51) MEN1KMT2ALMNAMAPTHTT
SCHEMBL16260534 0.86 LMNA (0.48) MEN1KMT2ALMNAMAPTHTT
SCHEMBL17080656 0.85 LMNA (0.52) MEN1KMT2ALMNAMAPTHTT
SCHEMBL26265704 0.85 LMNA (0.44) MEN1KMT2ALMNAMAPTHTT
SCHEMBL18355571 0.82 LMNA (0.49) MEN1KMT2ALMNAMAPTHTT
SCHEMBL18355975 0.80 MEN1 (0.42) MEN1KMT2ALMNAMAPTHTT
SCHEMBL30616857 0.80 LMNA (0.45) MEN1KMT2ALMNAMAPTHTT
SCHEMBL15999479 0.79 ALDH1A1 (0.53) MEN1KMT2ALMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230355800-A1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF THERAPEUTIC NANOPARTICLES Dantari, Inc. 2023-11-09 US disclosed
US-11738092-B2 Methods and compositions for synthesis of therapeutic nanoparticles Dantari, Inc. (US) 2023-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11738092-B2 Methods and compositions for synthesis of therapeutic nanoparticles CD47, CD44, HCCS MEN1 2996/4885KMT2A 3470/4885LMNA 1294/4885
US-20230355800-A1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF THERAPEUTIC NANOPARTICLES CD47, CD44, HCCS MEN1 2996/4885KMT2A 3470/4885LMNA 1294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.