SCHEMBL26266899

SCHEMBL26266899

O=C(CCCc1ccc2cccnc2n1)NCc1cc(-c2cccc(Cl)c2)no1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SUCNR1 Q9BXA5 20/20 1.00
▸ OXGR1 Q96P68 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26263380 0.90 SUCNR1 (0.81) SUCNR1OXGR1
SCHEMBL26264959 0.89 SUCNR1 (1.00) SUCNR1OXGR1
SCHEMBL26263382 0.86 SUCNR1 (0.82) SUCNR1OXGR1
SCHEMBL26263620 0.84 SUCNR1 (1.00) SUCNR1OXGR1
SCHEMBL26266523 0.83 SUCNR1 (1.00) SUCNR1OXGR1
SCHEMBL26265023 0.83 SUCNR1 (1.00) SUCNR1OXGR1
SCHEMBL26264929 0.83 SUCNR1 (0.71) SUCNR1OXGR1
SCHEMBL26266961 0.82 SUCNR1 (1.00) SUCNR1OXGR1
SCHEMBL26444172 0.75 SUCNR1 (0.73) SUCNR1OXGR1
SCHEMBL26263304 0.74 SUCNR1 (1.00) SUCNR1OXGR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023183776-A2 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION NEW YORK UNIVERSITY (US) 2023-09-28 — — WO disclosed
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION UNIV NEW YORK (US) 2023-09-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230293504-A1 TARGETING SUCNR1 TO REDUCE NEUROINFLAMMATION SUCNR1, SYNGR2, TSPO SUCNR1 1/4885OXGR1 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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