Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790366 | 0.83 | MTNR1A (0.57) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL23261971 | 0.80 | — | — | |
| Oxalic Acid SCHEMBL10340374 | 0.78 | MTNR1A (0.61) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| Maleic Acid SCHEMBL9790417 | 0.74 | MTNR1A (0.56) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL11019525 | 0.73 | MTNR1A (0.54) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL6890172 | 0.71 | HTR1A (0.65) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL10340261 | 0.71 | MTNR1A (0.49) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7716614 | 0.71 | HTR1A (0.64) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL26268093 | 0.70 | HTR1A (0.33) | MTNR1AMTNR1BHTR1AHTR1D | |
| SCHEMBL11021292 | 0.70 | MTNR1A (0.50) | MTNR1AMTNR1BHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295106-A1 | ERGOLINE-LIKE COMPOUNDS FOR PROMOTING NEURAL PLASTICITY | DELIX THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295106-A1 | ERGOLINE-LIKE COMPOUNDS FOR PROMOTING NEURAL PLASTICITY | GRIN1, GRIN2A, GRIN3B | MTNR1A 642/4885MTNR1B 332/4885HTR1A 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.