Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2626905 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CA2LMNASMN1; SMN2 | |
| SCHEMBL2626906 | 0.89 | SMN1; SMN2 (0.37) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL2626907 | 0.82 | GSTA1 (0.43) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL2626909 | 0.82 | GSTA1 (0.43) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL2626904 | 0.82 | GSTA1 (0.43) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL2626908 | 0.76 | SMN1; SMN2 (0.36) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL20121194 | 0.75 | SMN1; SMN2 (0.42) | ALDH1A1CYP3A4LMNASMN1; SMN2CRHBP | |
| SCHEMBL20121197 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1CYP3A4LMNASMN1; SMN2CRHBP | |
| SCHEMBL18505803 | 0.68 | CD69 (0.36) | LMNASMN1; SMN2CRHBPCRHR2HTT | |
| SCHEMBL1401911 | 0.68 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CA2LMNAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158088-B2 | Extractant compositions for co-extracting cesium and strontium, a method of separating cesium and strontium from an aqueous feed, and calixarene compounds | BATTELLE ENERGY ALLIANCE, LLC (US) | 2012-04-17 | — | — | US | disclosed |