SCHEMBL2627622

SCHEMBL2627622

Brc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.67
MAPK1 P28482 2/20 0.67
NR1H4 Q96RI1 2/20 0.64
NPC1 O15118 2/20 0.63
RAB9A P51151 2/20 0.63
NFKB1 P19838 1/20 0.63
NFKB2 Q00653 1/20 0.63
RELA Q04206 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
NR1H2 P55055 4/20 0.60
NR1H3 Q13133 4/20 0.60
DGAT1 O75907 1/20 0.60
CYP1A1 P04798 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP1B1 Q16678 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2161418 1.00 ALDH1A1 (0.67) ALDH1A1MAPK1NR1H4NPC1RAB9A
SCHEMBL2255716 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NR1H4NPC1RAB9A
SCHEMBL21382820 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NR1H4NPC1RAB9A
SCHEMBL17876525 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NR1H4NPC1RAB9A
SCHEMBL2252359 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NR1H4NPC1RAB9A
SCHEMBL2256284 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NR1H4NPC1RAB9A
SCHEMBL21849525 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NR1H4NPC1RAB9A
SCHEMBL21385053 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NR1H4NPC1RAB9A
SCHEMBL21384241 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NR1H4NPC1RAB9A
SCHEMBL29382228 0.98 ALDH1A1 (0.71) ALDH1A1MAPK1NR1H4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791420-A Binaphthyl amine derivative, and preparation method and application thereof 广东工业大学 2024-10-18 CN claimed
CN-116425764-B Triazine and carbazole-containing heat-activated delayed fluorescence macrocyclic molecule and preparation method and application thereof 上海大学 2024-05-31 CN claimed
CN-108864138-B Organic light-emitting micromolecular material of spiro-type donor containing sulfonyl and preparation method thereof 华南理工大学 2024-05-31 CN claimed
CN-118027030-A Preparation method of nitrogen-containing heterocyclic ring organic electronic transmission material 山东千铄新材料有限公司 2024-05-14 CN claimed
CN-117209440-A Binaphthyl amine derivative, and preparation method and application thereof 广东工业大学 2023-12-12 CN claimed
CN-116813834-B Flexible stretchable organic room-temperature phosphorescent material and preparation method thereof 南京邮电大学 2023-11-14 CN claimed
CN-116925073-A Nitrogen-containing heterocyclic ring organic electronic transmission material, preparation method and application 山东千铄新材料有限公司 2023-10-24 CN claimed
CN-116813834-A Flexible stretchable organic room-temperature phosphorescent material and preparation method thereof 南京邮电大学 2023-09-29 CN claimed
CN-116425764-A Triazine and carbazole-containing heat-activated delayed fluorescence macrocyclic molecule and preparation method and application thereof 上海大学 2023-07-14 CN claimed
CN-111484515-B Synthesis method of s-triazine pinacol borate 濮阳惠成电子材料股份有限公司 2023-04-14 CN claimed
CN-112939972-B Thermal activation delayed fluorescent material of chiral triptycene skeleton and preparation method and application thereof 中国科学院化学研究所 2022-06-21 CN claimed
CN-114031568-A Novel triazine derivative and synthetic method thereof 西安欧得光电材料有限公司 2022-02-11 CN claimed
CN-113845491-A Benzophenothiazine derivatives and process for their preparation 南京邮电大学 2021-12-28 CN claimed
CN-113527279-A Light-emitting film, preparation method thereof, light-emitting device and display device 京东方科技集团股份有限公司 2021-10-22 CN claimed
CN-112961157-A Indolocarbazole-based organic luminescent material and preparation method and application thereof 电子科技大学 2021-06-15 CN claimed
CN-110092800-B Thermal activation delayed fluorescence molecular material, synthetic method thereof and electroluminescent device 武汉华星光电半导体显示技术有限公司 2020-12-08 CN claimed
WO-2020237991-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MOLECULAR MATERIAL, SYNTHESIS METHOD THEREFOR, AND ELECTROLUMINESCENT DEVICE 武汉华星光电半导体显示技术有限公司 2020-12-03 WO claimed
US-20200381632-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MOLECULAR MATERIAL, A SYNTHESIZING METHOD THEREFOR, AND AN ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-12-03 US claimed
CN-111484515-A Synthesis method of s-triazine pinacol borate 濮阳惠成电子材料股份有限公司 2020-08-04 CN claimed
CN-110092800-A Thermal activation delayed fluorescence molecular material and its synthetic method, electroluminescent device 武汉华星光电半导体显示技术有限公司 2019-08-06 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200381632-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MOLECULAR MATERIAL, A SYNTHESIZING METHOD THEREFOR, AND AN ELECTROLUMINESCENT DEVICE FARSB, WEE1, WASF2 ALDH1A1 1783/4885MAPK1 2284/4885NR1H4 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.