Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13780507 | 0.86 | CYP19A1 (0.54) | CYP19A1HSP90AB1ALDH1A1LMNAHDAC1 | |
| SCHEMBL18179442 | 0.85 | CYP19A1 (0.52) | CYP19A1HSP90AB1ALDH1A1LMNAHDAC1 | |
| SCHEMBL846586 | 0.85 | CYP19A1 (0.52) | CYP19A1HSP90AB1ALDH1A1LMNAHDAC1 | |
| SCHEMBL14479459 | 0.80 | CYP19A1 (0.48) | CYP19A1HSP90AB1ALDH1A1LMNAHDAC1 | |
| SCHEMBL18183893 | 0.80 | CYP19A1 (0.48) | CYP19A1HSP90AB1ALDH1A1LMNAHDAC1 | |
| SCHEMBL3097402 | 0.79 | CYP19A1 (0.57) | CYP19A1HSP90AB1ALDH1A1LMNAHDAC1 | |
| SCHEMBL29055930 | 0.79 | CYP19A1 (0.60) | CYP19A1HSP90AB1HDAC1NPC1RAB9A | |
| SCHEMBL9871633 | 0.78 | CPB2 (0.44) | ALDH1A1 | |
| SCHEMBL18082681 | 0.77 | PTPRA (0.51) | ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL755889 | 0.77 | CYP19A1 (0.47) | CYP19A1HSP90AB1ALDH1A1LMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245027-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-04-25 | — | — | EP | disclosed |