SCHEMBL2628124

SCHEMBL2628124

O=C(c1ccc(Cl)cc1)c1ccc(Oc2ccc3ccc(Oc4ccc(C(=O)c5ccc(Oc6cccc7c(Oc8ccc(C(=O)c9ccc(Cl)cc9)cc8)cccc67)cc5)cc4)cc3c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.45
RHEB Q15382 1/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 2/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
SRD5A2 P31213 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
KDR P35968 2/20 0.41
BCL2 P10415 1/20 0.41
MCL1 Q07820 1/20 0.41
BAD Q92934 1/20 0.41
CHEK2 O96017 1/20 0.41
ELANE P08246 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
FABP2 P12104 1/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2628129 0.94 KDR (0.47) HPGDRHEBMAPTPOLBLMNA
SCHEMBL2628125 0.94 LMNA (0.43) HPGDRHEBMAPTPOLBLMNA
SCHEMBL2628155 0.92 KDR (0.47) HPGDRHEBMAPTPOLBLMNA
SCHEMBL822946 0.90 HPGD (0.54) HPGDRHEBMAPTPOLBLMNA
SCHEMBL2628140 0.89 KDR (0.49) HPGDRHEBPOLBSRD5A2MEN1
SCHEMBL822643 0.89 HPGD (0.56) HPGDMAPTPOLBSRD5A2MEN1
SCHEMBL2628134 0.88 LMNA (0.50) HPGDMAPTPOLBLMNAHTT
SCHEMBL822835 0.85 HPGD (0.59) HPGDMAPTPOLBSRD5A2CHEK2
SCHEMBL9452121 0.85 MEN1 (0.49) HPGDRHEBMAPTPOLBLMNA
SCHEMBL822859 0.84 MAPT (0.57) HPGDMAPTPOLBLMNASRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163406-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-04-24 US disclosed
US-20080160381-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2008-07-03 US disclosed