Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628146 | 0.94 | KDR (0.45) | SIRT2SIRT1SIRT3HSD17B1HSD17B2 | |
| SCHEMBL2628157 | 0.91 | CYP1A2 (0.43) | SIRT2SIRT1SIRT3HSD17B1HSD17B2 | |
| SCHEMBL2628140 | 0.86 | KDR (0.49) | KDRKMT2APOLBSRD5A2AURKA | |
| SCHEMBL2628155 | 0.84 | KDR (0.47) | SIRT2SIRT1SIRT3KDRLMNA | |
| SCHEMBL822847 | 0.84 | LMNA (0.53) | SIRT2SIRT1SIRT3HSD17B1HSD17B2 | |
| SCHEMBL2628129 | 0.83 | KDR (0.47) | KDRLMNAHTTKMT2APOLB | |
| SCHEMBL822846 | 0.82 | LMNA (0.59) | HSD17B1HSD17B2ALDH1A1LMNAMMP13 | |
| SCHEMBL15760407 | 0.81 | SRD5A2 (0.58) | HSD17B1HSD17B2ALDH1A1LMNAMMP13 | |
| SCHEMBL822845 | 0.79 | LMNA (0.55) | HSD17B1HSD17B2ALDH1A1LMNAMMP13 | |
| SCHEMBL13871403 | 0.79 | CYP1A2 (0.52) | KDRALDH1A1LMNAHTTAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163406-B2 | Membrane-electrode assembly for solid polymer electrolyte fuel cell | HONDA MOTOR CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20080160381-A1 | MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL | HONDA MOTOR CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |