⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25831178 | 0.88 | DPP4 (0.47) | — | |
| SCHEMBL12386819 | 0.83 | — | — | |
| SCHEMBL16978921 | 0.82 | — | — | |
| SCHEMBL13469511 | 0.80 | SMPD1 (0.44) | — | |
| SCHEMBL2628202 | 0.80 | — | — | |
| SCHEMBL24029526 | 0.80 | MAPK14 (0.45) | — | |
| SCHEMBL20047038 | 0.80 | MAPK14 (0.45) | — | |
| SCHEMBL12386625 | 0.79 | DPP4 (0.43) | — | |
| SCHEMBL255391 | 0.78 | — | — | |
| SCHEMBL19500403 | 0.78 | DPP4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682954-B2 | Phenanthridine derivatives, preparation methods and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-20 | — | — | US | claimed |
| US-20160083364-A1 | Phenanthridine Derivatives, Preparation Methods and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-24 | — | — | US | claimed |
| EP-4077334-B1 | FUROINDAZOLE DERIVATIVES | BAYER AG (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2024100452-A2 | HETEROCYCLIC COMPOUNDS AS STING AGONISTS | LEGOCHEM BIOSCIENCES, INC. (KR) | 2024-05-16 | — | — | WO | disclosed |
| US-20200377920-A1 | METHOD AND COMPOSITION FOR BIOCATALYTIC PROTEIN-OLIGONUCLEOTIDE CONJUGATION AND PROTEIN-OLIGONUCLEOTIDE CONJUGATE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2020-12-03 | — | — | US | disclosed |
| US-10738338-B2 | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate | The Research Foundation for the State University (US) | 2020-08-11 | — | — | US | disclosed |
| EP-3492919-A2 | QUINONE METHIDE ANALOG SIGNAL AMPLIFICATION | Ventana Medical Systems, Inc. (US) | 2019-06-05 | — | — | EP | disclosed |
| US-20180112245-A1 | METHOD AND COMPOSITION FOR BIOCATALYTIC PROTEIN-OLIGONUCLEOTIDE CONJUGATION AND PROTEIN-OLIGONUCLEOTIDE CONJUGATE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2018-04-26 | — | — | US | disclosed |
| US-20180112245-A1 | METHOD AND COMPOSITION FOR BIOCATALYTIC PROTEIN-OLIGONUCLEOTIDE CONJUGATION AND PROTEIN-OLIGONUCLEOTIDE CONJUGATE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2018-04-26 | — | — | US | disclosed |
| US-20170362201-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2017-12-21 | — | — | US | disclosed |
| US-9815818-B2 | Cot modulators and methods of use thereof | GILEAD SCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9682954-B2 | Phenanthridine derivatives, preparation methods and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2017-06-20 | — | — | US | disclosed |
| US-20170008873-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
| US-8871940-B2 | Unsymmetrical bisazides for chemoselective sequential ligation | The Florida State University Research Foundation, Inc. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140018541-A1 | UMSYMMETRICAL BISAZIDES FOR CHEMOSELECTIVE SEQUENTIAL LIGATION | The Florida State University Research Foundation, Inc. (US) | 2014-01-16 | — | — | US | disclosed |
| US-8114872-B2 | Triazolyl aminopyrimidine compounds | ELI LILLY AND COMPANY (US) | 2012-02-14 | — | — | US | disclosed |
| US-8063035-B2 | Triazolyl aminopyrimidine compounds | ELI LILLY AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-20100130466-A1 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY | 2010-05-27 | — | — | US | disclosed |
| US-20100087431-A1 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY | 2010-04-08 | — | — | US | disclosed |