Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23658266 | 1.00 | LMNA (0.40) | LMNASLC22A6KDM4CKDM4APHF8 | |
| SCHEMBL10631897 | 0.92 | TSHR (0.46) | LMNASLC22A6KDM4CKDM4APHF8 | |
| SCHEMBL27371780 | 0.88 | TSHR (0.46) | LMNASLC22A6KDM4CKDM4APHF8 | |
| SCHEMBL26354668 | 0.85 | KDM4C (0.44) | LMNASLC22A6KDM4CKDM4APHF8 | |
| SCHEMBL11210263 | 0.83 | EPHX2 (0.55) | LMNAPPARGPPARDPPARA | |
| Succinic Acid SCHEMBL8005658 | 0.82 | LMNA (0.45) | LMNAKDM4CKDM4APHF8KDM2A | |
| SCHEMBL23658267 | 0.80 | — | — | |
| Edetol SCHEMBL26665875 | 0.79 | KDM4C (0.39) | LMNASLC22A6KDM4CKDM4APHF8 | |
| SCHEMBL9492420 | 0.79 | KDM4E (0.36) | TSHRALDH1A1 | |
| SCHEMBL436610 | 0.79 | KDM4E (0.36) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178167-A1 | ASYMMETRIC PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2023-09-21 | — | — | WO | disclosed |