Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Levulinic Acid SCHEMBL16666875 | 0.91 | LMNA (0.58) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Acetic Acid SCHEMBL7780427 | 0.84 | KDM4E (0.39) | FFAR3KDM4EALDH1A1 | |
| Acetic Acid SCHEMBL22788463 | 0.84 | KDM4E (0.39) | FFAR3KDM4EALDH1A1 | |
| Hydrogen Peroxide SCHEMBL28243254 | 0.84 | TSHR (0.41) | LMNAKDM4EALDH1A1 | |
| Trolamine SCHEMBL9395595 | 0.83 | PHF8 (0.35) | LMNAEGLN1ALKBH5SUCNR1SLC15A2 | |
| Glycine SCHEMBL28240235 | 0.83 | GLRA1 (0.48) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL23658266 | 0.82 | LMNA (0.40) | LMNAKDM2APHF8KDM4CKDM4A | |
| SCHEMBL26285100 | 0.82 | LMNA (0.40) | LMNAKDM2APHF8KDM4CKDM4A | |
| Lactic Acid SCHEMBL16667262 | 0.82 | TP53 (0.58) | KDM4E | |
| Decanoic Acid SCHEMBL16667033 | 0.82 | GPR84 (0.63) | LMNACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974508-B | Anti-whiskering stain-resistant waterproof decoration integrated mortar and preparation process thereof | 宏源防水科技集团有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-115974508-A | Anti-efflorescence stain-resistant waterproof decoration integrated mortar and preparation process thereof | 宏源防水科技集团有限公司 | 2023-04-18 | — | — | CN | disclosed |
| EP-0821712-A4 | PROCESS FOR PREPARING AN IMPROVED LOW-DUSTING, FREE-FLOWING PIGMENT | KERR MCGEE CHEMICAL LLC (US) | 2000-07-12 | — | — | EP | disclosed |
| US-5908498-A | Process for preparing an improved low-dusting, free-flowing pigment | KERR-MCGEE CHEMICAL LLC (US) | 1999-06-01 | — | — | US | disclosed |
| US-5830929-A | METAL DIALKYL SULFOSUCCINATE | KERR-MCGEE CHEMICAL CORPORATION | 1998-11-03 | — | — | US | disclosed |
| US-5733365-A | Process for preparing an improved low-dusting, free-flowing pigment | KERR-MCGEE CORPORATION (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0821712-A1 | PROCESS FOR PREPARING AN IMPROVED LOW-DUSTING, FREE-FLOWING PIGMENT | KERR-MCGEE CHEMICAL CORPORATION (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1997030127-A1 | PROCESS FOR PREPARING AN IMPROVED LOW-DUSTING, FREE-FLOWING PIGMENT | KERR-MCGEE CHEMICAL CORPORATION (US) | 1997-08-21 | — | — | WO | disclosed |
| EP-0761741-A1 | Pigments with improved dispersibility in thermoplastic resins | KERR-MCGEE CHEMICAL CORPORATION (US) | 1997-03-12 | — | — | EP | disclosed |
| EP-0761740-A1 | Treatment of pigments for improved dispersibility and concentration in thermoplastic resins | KERR-MCGEE CHEMICAL CORPORATION (US) | 1997-03-12 | — | — | EP | disclosed |
| US-5567754-A | SURFACE TREATING INORGANIC PIGMENTS WITH A PARTIAL ESTER POLYOL OF AN UNSATURATED MONOCARBOXYLIC ACID TREATING AGENT | KERR-MCGEE CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0345267-A1 | IMPROVED TITANIUM DIOXIDE PIGMENTS. | KERR MC GEE CHEM CORP (US) | 1989-12-13 | — | — | EP | disclosed |
| WO-1988005454-A1 | IMPROVED TITANIUM DIOXIDE PIGMENTS | KERR-MCGEE CHEMICAL CORPORATION (US) | 1988-07-28 | — | — | WO | disclosed |
| US-4752340-A | SURFACE TREATMENT WITH AN AMINE SALT OF A POLYPROTIC ACID | KERR-MCGEE CHEMICAL CORPORATION (US) | 1988-06-21 | — | — | US | disclosed |