Bromisovalum

Bromisovalum

SCHEMBL262870

CC(C)C(Br)C(=O)NC(N)=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.40
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.31
ALDH1A1 P00352 2/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbromal SCHEMBL13723954 0.81 HTT (0.32) HTT
SCHEMBL11411566 0.80
Bromisovalum SCHEMBL6723826 0.76 ALDH1A1 (0.45) ALDH1A1MEN1KMT2A
SCHEMBL3652416 0.75 CRBN (0.43) CRBNRECQLALDH1A1MEN1LMNA
SCHEMBL9428999 0.74
SCHEMBL28728166 0.73 DPP4 (0.48) CRBNRECQLALDH1A1MEN1LMNA
SCHEMBL10575445 0.73 CRBN (0.42) CRBNRECQLALDH1A1MEN1LMNA
SCHEMBL28728167 0.73 DPP4 (0.48) CRBNRECQLALDH1A1MEN1LMNA
SCHEMBL23691240 0.72
SCHEMBL4411230 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240398855-A1 BROMIDE SOURCE FOR USE IN TREATING AUTISM SPECTRAL DISORDER INST NAT SANTE RECH MED (FR) 2024-12-05 US claimed
US-12036237-B2 Bromide source for use in treating autism spectral disorder INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2024-07-16 US claimed
US-20230256009-A1 BROMIDE SOURCE FOR USE IN TREATING AUTISM SPECTRAL DISORDER INSERM, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2023-08-17 US claimed
US-11666599-B2 Bromide source for use in treating autism spectral disorder INSERM, INTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2023-06-06 US claimed
US-20220273600-A1 LITHIUM SALTS OF N-SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2022-09-01 US claimed
US-20210106613-A1 BROMIDE SOURCE FOR USE IN TREATING AUTISM SPECTRAL DISORDER INRA, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) 2021-04-15 US claimed
EP-3651759-A1 LITHIUM SALTS OF N-SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF Syneurx International (Taiwan) Corp. (TW) 2020-05-20 EP claimed
EP-3544599-A1 BROMIDE SOURCE FOR USE IN TREATING AUTISM SPECTRAL DISORDER (INSERM) Institut National de la Santé et de la Recherche Médicale (FR) 2019-10-02 EP claimed
CN-110204460-A A kind of bromisoval fabrication processing 华润双鹤利民药业(济南)有限公司 2019-09-06 CN claimed
US-10226442-B2 Lithium salts of N-substituted glycine compounds and uses thereof SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2019-03-12 US claimed
EP-0729748-A1 PROCESS FOR PRODUCING STABLE MEDICINAL COMPOSITION, AND PHARMACEUTICAL PREPARATION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1996-09-04 EP claimed
US-5374608-A Compositions containing adducts and surfactants UNION OIL COMPANY OF CALIFORNIA (US) 1994-12-20 US claimed
US-5354563-A Water dispersion containing ultrafine particles of organic compounds RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) 1994-10-11 US claimed
US-5288692-A Systemic herbicides and methods of use UNION OIL COMPANY OF CALIFORNIA (US) 1994-02-22 US claimed
EP-0209403-B1 PROCESS FOR PREPARING ULTRAFINE PARTICLES OF ORGANIC COMPOUNDS Research Development Corporation of Japan (JP) 1991-10-23 EP claimed
US-4913865-A Process for preparing ultrafine particles of organic compounds RESEARCH DEVELOPMENT CORP OF JAPAN (JP) 1990-04-03 US claimed
US-4805340-A Humane glue trap for rats, mice and other vermin having carbomal in the bait TAMBY CHEMICAL CORP. (US) 1989-02-21 US claimed
EP-0209403-A2 Process for preparing ultrafine particles of organic compounds Research Development Corporation of Japan (JP) 1987-01-21 EP claimed
US-4466953-A Polymeric diffusion matrix KEY PHARMACEUTICALS, INC. (US) 1984-08-21 US claimed
US-3960757-A HYDROPHOBIC TOYO JOZO CO., LTD. (JA) 1976-06-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273600-A1 LITHIUM SALTS OF N-SUBSTITUTED GLYCINE COMPOUNDS AND USES THEREOF SLC1A2, SLC6A5, SLC1A1 CRBN 2865/4885HTT 250/4885RECQL 2022/4885
US-10226442-B2 Lithium salts of N-substituted glycine compounds and uses thereof SLC1A2, SLC6A5, SLC1A1 CRBN 2865/4885HTT 250/4885RECQL 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.