Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | POLG | P54098 | 1/20 | 0.31 |
| ▸ | DCK | P27707 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22475028 | 0.88 | ALB (0.34) | ALB | |
| SCHEMBL26805785 | 0.84 | ALB (0.38) | ALBDCK | |
| SCHEMBL26800847 | 0.81 | ALB (0.38) | ALB | |
| SCHEMBL26800920 | 0.80 | ALB (0.38) | ALB | |
| SCHEMBL20194004 | 0.80 | ALB (0.38) | ALBPOLG | |
| SCHEMBL26270678 | 0.77 | POLG (0.47) | POLG | |
| SCHEMBL27851822 | 0.75 | ALB (0.43) | ALBPOLGDCK | |
| SCHEMBL19993745 | 0.74 | POLG (0.43) | POLG | |
| SCHEMBL20754407 | 0.74 | POLG (0.43) | POLG | |
| SCHEMBL26277287 | 0.73 | ALB (0.37) | ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230374058-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. | 2023-11-23 | — | — | US | disclosed |
| US-20230295212-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS INC (US) | 2023-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295212-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | EHMT1, POLRMT, RNASE1 | ALB 4486/4885POLG 40/4885DCK 146/4885 |
| US-20230374058-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | EHMT1, POLRMT, RNASE1 | ALB 4486/4885POLG 40/4885DCK 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.